Reversing Insulin Resistance
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Vickie Petz Kasper, M.D.
Diplomate of the American Board of Obstetrics and Gynecology – Retired
Diplomate of the American Board of Lifestyle Medicine – Retired
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Insulin Resistance: What to Do When Your Labs Come Back Wrong
The first time my labs showed signs of insulin resistance, I was convinced it was an error. I exercised regularly. I ate well. This wasn’t supposed to happen to me. So I had them repeated — and sure enough, my numbers were better. Until they weren’t.
Looking back, that first result was probably my body’s earliest warning that I have a genetic tendency toward diabetes. But even if I’d taken it seriously, I’m not sure I would have known what to do. That’s exactly why I’m writing this today.
A Little History First
The first real clue that type 2 diabetes could be reversed came from the operating room. In the mid-90s, researchers observed something surprising in patients who had bariatric surgery — not only were they losing weight, their type 2 diabetes was disappearing, sometimes before they’d lost significant weight. That told researchers something important: this wasn’t just about calories.
That discovery eventually led to research on whether aggressive dietary changes could produce the same effect. Some of those early approaches were pretty extreme — not exactly something most people could sustain. And that’s been the pattern for decades. People start radical diets, can’t stick with them, and end up back where they started.
It wasn’t until 2016 that major health organizations, including the WHO, formally accepted that type 2 diabetes is reversible through lifestyle intervention. And it took another five years or so for that idea to really filter into everyday medicine. The good news is we’re there now — and you don’t have to do anything radical to start moving in the right direction.
Yes, Weight and Exercise Matter — But Stay With Me
I know. You’ve heard it before. Diet and exercise. But before you click away, let me tell you what that actually means, because it’s probably not what you think.
Even a 10% reduction in body weight can meaningfully improve insulin resistance. And exercise helps in two ways: it makes your muscles soak up blood sugar even when insulin levels are low, and over time it makes your body more sensitive to insulin overall. Both strength training and aerobic exercise have benefits, but even a short walk after meals makes a measurable difference — and it’s the most doable place to start.
So yes, put down your fork after dinner and go for a walk. That one habit alone is worth something.
What to Actually Eat
There isn’t one perfect diet for insulin resistance, but there are some clear principles.
Fiber is your best friend. You need at least 30 grams a day, and you can only get it from plants — fruits, vegetables, beans, legumes, nuts, seeds, and whole grains. The more those foods resemble the way nature made them, the better. Multigrain bread on a package label sounds healthy, but it usually just means multiple processed grains. Whole grain means something different — look for that instead.
Eat in the right order. This one is surprisingly powerful and surprisingly easy. Eat your fiber first — vegetables, beans, nuts. Then protein and fats. Save the simple carbs for last. You don’t have to change what’s on your plate, just the order you eat it. Research shows this can meaningfully reduce your blood sugar response to a meal.
Fruit is not the enemy. People with insulin resistance are often told to avoid fruit because of the sugar. But whole fruit comes packaged with fiber and polyphenols that actually help counter the inflammatory response to sugar. Studies show that people who eat fruit regularly have a lower risk of developing insulin resistance. Berries, kiwis, and clementines are especially good choices. Just eat them as close to their natural form as possible — a blueberry cobbler doesn’t count.
Watch your saturated fat. Full fat dairy, red meat, and processed meats like bacon can worsen insulin resistance and interfere with the function of the beta cells in your pancreas that produce insulin. Think of your daily saturated fat intake like a golf handicap — the lower the better.
Go heavy on plants. A friend of mine had tried everything to get her HbA1c down — her weight was healthy, she didn’t drink, she exercised, slept well, and managed stress. Nothing moved the needle. She shifted to a whole food, plant-based diet — not strict vegetarian, more like 80/20 — and not only did her A1C normalize, her cholesterol dropped significantly too. Most people can’t make a change that dramatic and make it stick. But nearly everyone can make smaller changes that start shifting things in the right direction.
Don’t Underestimate Stress and Sleep
This is the part people often overlook. Chronic stress keeps cortisol levels elevated, and high cortisol promotes visceral fat — the kind that collects around your organs and drives insulin resistance. Poor sleep makes this worse by throwing off the hormones that regulate hunger and fullness, leading to cravings that make healthy eating harder. It all feeds on itself in a vicious loop.
Stress management and restorative sleep aren’t lifestyle extras. They’re part of the treatment. We go much deeper on both inside the Lab, because knowing they matter is one thing — having an actual plan for managing them is where real change happens.
What Happened When I Put This Into Practice
My energy improved. My focus sharpened. My productivity went up. My mood stabilized. My skin looked better. And the biggest change of all? My appetite stopped feeling out of control.
That last one changed everything.
So Where Do You Start?
You don’t have to overhaul your life overnight. Start here:
Add more fiber and eat it first. Take a walk after meals. Get serious about sleep. Find one stress management practice that actually works for you. And if you eat meat, start shifting the balance toward more plants.
Small changes in the right direction still count as the right direction.
Want to Go Deeper?
Inside the Healthy Looks Great on You LAB, we’re doing a focused deep dive on balancing blood sugar and building better energy — with meal plans, recipes, and a fiber challenge that makes this feel genuinely doable. You’ll learn not just what to do, but how to make it stick, alongside a community of women on the same journey.
This month you can join for just $19/month.
👉 Join the Lab at healthylooksgreatonyou.com/the-lab
Your future self will thank you.
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