September 4, 2026

Episode 243: Is Melatonin Bad for Your Heart?

65% of adults in the U.S. have taken melatonin. Does it work and is it safe? New studies linking melatonin and heart failure should make us pause before taking this supplement.

Dr. Vickie

Is Melatonin Bad for Your Heart? What New Research Reveals

For years, melatonin has been the go-to fix when sleep won’t come. It might be something you grab off the shelf without a second thought. But new research is raising real questions about what it might be doing to your heart, and most people taking it have no idea.

In this episode, Dr. Vickie takes you to “mini medical school” to break down what’s actually happening in your body — and why the story is more complicated than “natural sleep aid, take before bed.”

What You’ll Learn

Melatonin isn’t what you think it is.

It’s not a sleeping pill, instead it’s a signal. Most of the melatonin in your body is made in your gut. Your brain makes about 0.3mg of it a night.

Your supplement probably contains way more than that.

Most over-the-counter bottles contain 3 – 10mg, which is 10 to 30 times what your body naturally produces. And because the FDA doesn’t regulate supplements the same way it regulates medications, the actual amount in the bottle often doesn’t match the label at all.

Timing matters more than you’d think.

Taking melatonin right at bedtime — the way most people do — isn’t actually how it’s meant to work. Dr. Vickie explains the timing mistake almost everyone makes, and what to do instead.

New research links long-term use to heart risk.

Preliminary findings presented at the American Heart Association’s Scientific Sessions found that people who’d taken melatonin for a year or more had a 90% higher risk of heart failure compared to non-users. It’s not proof melatonin causes heart problems — but it’s a signal worth paying attention to.

Food can do some of this work instead.

Your gut is already making melatonin from the foods you eat. Dr. Vickie explains the connection between diet, your gut microbiome, and better sleep — no supplement required.

Get the Free Guide

Want a place to start tonight? Grab Dr. Vickie’s free guide, 3 Simple Strategies to Sleep Smarter — plus a bonus sleep-friendly recipe built around real food sources of melatonin and magnesium.

👉 healthylooksgreatonyou.com/sleep

LINK to NIH study: https://pubmed.ncbi.nlm.nih.gov/27855744/

This information is for educational purposes only and is not intended to be a substitute for medical advice.

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